In other circumstances I would definitely chose different bet, but my main reason for chosing the home side is because that Valencia have quite distance from the fourt team on the table (five points) and their aspirations for this season are definitely to keep this third place on the table because there are no chances to overcome Real Madrid or Barcelona, while this place will secure their direct place in the Champions league group stage. Another important thing that affect on this match is the second-leg in the Cup which should be played in the next midweek against Barcelona at Camp Nou and Valencia should give their maximum if they want to overcome the first result (1-1) from Mestalla.
So, I am quite sure that Valencia will play with many changes in the first team, because they are so close to the Cup final and if they succeed to advance against Barcelona they will have the Cup title with one hand. However, that has to be proven yet by this side and fresh legs should be first important thing on the mind.
On the contrary, Atletico have finally found the right rytham and have reached three important wins in a row. They are back in contention for the fourth place on the table, the distance between them and Levante is only two points, and the main reason for that is their strong display this season in front of their fans. Tomorrow, I have no doubts that Vicente Calderon will be "fully loaded", something that will be huge boost for the home side and another impressive performance against the less-interested side should be on the way...